LINAPIL D 10 TABLET

💊 Dapagliflozin 10 mg + Linagliptin 5 mg Tablet: Modern Dual Therapy for Type 2 Diabetes

🔹 What is Dapagliflozin + Linagliptin Tablet?

This fixed-dose combination is used to manage Type 2 Diabetes Mellitus (T2DM) in adults who need better blood sugar control. It combines two complementary medications:

• Dapagliflozin (10 mg): An SGLT2 inhibitor that works by promoting glucose excretion through urine, thereby lowering blood sugar and reducing body weight and blood pressure.

• Linagliptin (5 mg): A DPP-4 inhibitor that increases incretin levels, helping boost insulin release and suppress glucagon post meals.

Together, they target different pathways to achieve better glycemic control with low risk of hypoglycemia.

🧪 Ingredients

• Active ingredients:

  • Dapagliflozin Propanediol Monohydrate equivalent to 10 mg of Dapagliflozin

  • Linagliptin 5 mg

• Inactive ingredients (may vary by brand):

  • Microcrystalline cellulose

  • Magnesium stearate

  • Colloidal silicon dioxide

  • Hypromellose

  • Titanium dioxide

Always check the leaflet for specific excipients, especially for allergies.

💡 How to Use

• Dosage: Typically once daily, with or without food.

• Timing: Try to take it at the same time each day, usually in the morning.

• Hydration: Drink plenty of water to avoid dehydration from increased urination caused by Dapagliflozin.

Do not crush or chew. Swallow the tablet whole with water.

⚠️ Common Side Effects

From Dapagliflozin:

• Frequent urination

• Thirst or dry mouth

• Urinary tract infections

• Genital infections (especially in women)

From Linagliptin:

• Nasopharyngitis (cold symptoms)

• Headache

• Joint pain

🚨 Serious Side Effects

Seek urgent care if you notice:

• Ketoacidosis (rare but life-threatening): Nausea, vomiting, abdominal pain, confusion, and difficulty breathing

• Severe dehydration

• Pancreatitis: Severe abdominal pain, nausea

• Hypoglycemia: Especially when combined with insulin or sulfonylureas

• Allergic reactions: Swelling, rash, difficulty breathing

🩺 Monitoring & Follow-Up

Patients require regular follow-up:

• Blood glucose & HbA1c: Every 3–6 months

• Kidney function (eGFR): At baseline and periodically (important for Dapagliflozin use)

• Urinary tract health

• Liver enzymes if symptoms indicate possible damage

• Body weight and blood pressure may also be tracked for additional benefits

⚠️ Warnings & Precautions

• Not for Type 1 Diabetes or diabetic ketoacidosis

• Avoid in severe renal impairment (eGFR < 30 mL/min/1.73m²)

• Use caution in elderly (higher risk of dehydration)

• Increased risk of genital infections; maintain proper hygiene

• Pregnancy & Lactation: Not recommended unless clearly needed

📝 Summary

The Dapagliflozin 10 mg + Linagliptin 5 mg tablet is an effective once-daily oral therapy for adults with Type 2 Diabetes, offering benefits like weight loss, blood pressure reduction, and low hypoglycemia risk. While generally well-tolerated, it requires monitoring for kidney function, hydration, and rare complications like ketoacidosis or pancreatitis. Patients must maintain good hygiene, stay hydrated, and attend regular follow-ups to ensure safety and effectiveness.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.