➤ ETORICOXIB 60 mg TABLET: RELIEF WITH PRECISION

Overview

Etoricoxib 60 mg is a prescription medication belonging to a class of drugs known as COX-2 selective inhibitors. It is primarily used to manage pain and inflammation associated with various chronic and acute musculoskeletal conditions. Unlike traditional NSAIDs, Etoricoxib targets the COX-2 enzyme selectively, minimizing gastrointestinal side effects while offering potent anti-inflammatory and analgesic effects.

Key Uses

Etoricoxib 60 mg is indicated for:

• Osteoarthritis (OA) – Long-term relief of joint pain and stiffness.

• Rheumatoid Arthritis (RA) – Management of inflammation and swelling.

• Ankylosing Spondylitis (AS) – Alleviates spinal pain and stiffness.

• Gouty Arthritis – Short-term treatment for acute gout flare-ups.

• Chronic Low Back Pain – As part of a comprehensive treatment plan.

Mechanism of Action

Etoricoxib works by inhibiting the COX-2 enzyme, which plays a key role in the production of prostaglandins, substances that cause inflammation, pain, and swelling. By sparing the COX-1 enzyme (which protects the stomach lining), Etoricoxib reduces pain without significantly increasing the risk of gastric ulcers or bleeding, a common concern with non-selective NSAIDs.

Dosage and Administration

• Typical dose: 60 mg once daily.

• Route: Oral, with or without food.

• Special considerations:

  • In acute gout, higher doses (up to 120 mg) may be used short-term.

  • Not recommended for long-term use in individuals with significant cardiovascular risk.

Always follow your healthcare provider’s instructions regarding dosage and duration.

Benefits

• Rapid onset of action – noticeable relief often within hours.

• Once-daily dosing – enhances compliance.

• Lower risk of gastrointestinal side effects compared to traditional NSAIDs.

• No significant effect on platelet function, thus less risk of bleeding compared to aspirin.

Possible Side Effects

Though generally well-tolerated, Etoricoxib may cause:

• Mild side effects: Headache, dizziness, heartburn, nausea.

• Serious risks (rare): Elevated blood pressure, cardiovascular events (especially with prolonged use), liver enzyme abnormalities, and kidney impairment.

Precautions

• Avoid in patients with:

  • Active peptic ulcers or bleeding disorders.

  • Severe hepatic or renal impairment.

  • Established ischemic heart disease, stroke, or peripheral arterial disease.

• Caution in elderly patients and those on diuretics or other NSAIDs.

• Not approved for use in children or adolescents under 16.

Drug Interactions

May interact with:

• Warfarin – increased risk of bleeding.

• ACE inhibitors / ARBs – may reduce kidney function.

• Diuretics – potential for fluid retention and hypertension.

• Methotrexate – may elevate blood levels of methotrexate.

Conclusion

Etoricoxib 60 mg tablet offers a targeted approach to pain management, especially for individuals with chronic inflammatory conditions. While it offers a safer gastrointestinal profile than traditional NSAIDs, it must be used cautiously due to potential cardiovascular and renal risks. Always use under medical supervision and report any unusual symptoms promptly.

 Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.