Description
🔷 PROSTATIC COMFORT TABLET 🔷
Targeted Relief for Urinary Obstruction and Prostate Inflammation
💊 Composition (Per Modified Release Tablet)
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Tamsulosin Hydrochloride – 0.4 mg
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Deflazacort – 30 mg
🧠 Overview
This dual-action tablet provides an effective solution for Benign Prostatic Hyperplasia (BPH) and chronic inflammatory conditions of the prostate or lower urinary tract. Tamsulosin improves urinary flow by relaxing smooth muscle in the prostate and bladder neck, while Deflazacort reduces inflammation and edema in prostatic tissue. This combination addresses both mechanical obstruction and inflammatory discomfort, offering a comprehensive therapeutic approach for male urological conditions.
🔬 Mechanism of Action
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Tamsulosin (0.4 mg):
A uroselective alpha-1 adrenergic blocker, Tamsulosin primarily targets the alpha-1A receptors in the prostate and lower urinary tract. By relaxing smooth muscles, it improves urinary flow, reduces bladder outlet resistance, and alleviates LUTS (Lower Urinary Tract Symptoms) like frequency, urgency, and weak stream. Its selectivity minimizes cardiovascular side effects. -
Deflazacort (30 mg):
A synthetic glucocorticoid corticosteroid with strong anti-inflammatory and immunosuppressive properties. It reduces prostatic swelling, suppresses inflammatory cytokines, and limits immune cell infiltration. Compared to traditional steroids, Deflazacort is known for fewer metabolic side effects and lower risk of bone demineralization.
🎯 Indications
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Benign Prostatic Hyperplasia (BPH) with inflammation
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Chronic Prostatitis or Prostatodynia
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Pelvic Inflammatory Syndrome in men
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Post-surgical urinary obstruction and tissue swelling
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Steroid-responsive urological inflammation
✅ Therapeutic Benefits
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Dual mechanism: relieves urinary obstruction and controls inflammation
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Enhances bladder emptying and reduces nocturia and hesitancy
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Short-term steroid use helps resolve acute inflammatory flares
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Improves overall urinary comfort and quality of life
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Offers rapid symptom control in conditions with prostatic edema or autoimmune involvement
💊 Dosage & Administration
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Adults (Male ≥18 years):
1 tablet once daily, preferably after the same meal each day
Best taken in the evening to reduce the risk of orthostatic hypotension -
Duration of Deflazacort use should be short-term, tapered as appropriate
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Dosage should always follow physician supervision
⚠️ Precautions & Side Effects
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Common Side Effects:
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Postural dizziness (Tamsulosin)
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Mild weight gain, insomnia, or gastric irritation (Deflazacort)
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Headache, ejaculatory disturbances
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Serious Side Effects (rare with proper use):
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Prolonged corticosteroid use: adrenal suppression, muscle weakness, hyperglycemia
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Tamsulosin-related hypotension in susceptible individuals
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Caution in diabetics, hypertensive, or peptic ulcer patients
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Monitoring Required For:
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Blood glucose and blood pressure
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Prostate-specific antigen (PSA) levels
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Adrenal function with extended corticosteroid therapy
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🛡️ Storage & Handling
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Store below 25°C in a dry place
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Protect from light and moisture
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Keep out of reach of children
📝 Conclusion
This Tamsulosin + Deflazacort combination is a strategic dual-therapy for patients with urinary obstruction linked to prostatic inflammation. By combining urodynamic improvement with anti-inflammatory action, it ensures better urinary flow, pain reduction, and faster recovery—making it ideal for both acute flare-ups and short-term management in BPH-related disorders.
Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.
