Name: TOLVASCA 15 TABLET
Brand: Glenmark Pharmaceuticals Ltd
SKU: 20880
Availability: InStock

Description

💊 Tolvaptan 15 mg Tablet: Comprehensive Overview

🔹 What is Tolvaptan 15 mg?

Tolvaptan is a vasopressin V2-receptor antagonist used to treat conditions associated with low sodium levels in the blood (hyponatremia) and to slow kidney function decline in adults with autosomal dominant polycystic kidney disease (ADPKD). It helps the kidneys remove excess water from the body without losing sodium.

🔸 Ingredients

Active Ingredient: Tolvaptan 15 mg
Inactive Ingredients: Lactose monohydrate, maize starch, hydroxypropyl cellulose, magnesium stearate, and others (specific excipients may vary by brand).

💡 How to Use Tolvaptan

Dosage: Typically taken once daily, preferably in the morning, with or without food. Your doctor will adjust the dose based on your condition.
Hydration: Patients must drink water frequently to prevent dehydration, as Tolvaptan increases urine output.
Adherence: Do not stop or adjust the dose without consulting your doctor.

⚠️ Common Side Effects

Frequent urination
Thirst or dry mouth
Tiredness
Constipation
Dry skin

These are generally mild and often subside as your body adjusts to the medication.

🚨 Serious Side Effects

Seek immediate medical attention if you experience:

Liver damage symptoms: Yellowing of the skin/eyes, dark urine, upper right abdominal pain.
Severe dehydration: Dizziness, low blood pressure, confusion.
Hypernatremia: High blood sodium levels causing restlessness, muscle twitching, or seizures.

🔍 Monitoring & Follow-Up

Due to potential liver toxicity, regular monitoring is essential:

Liver Function Tests (LFTs): Every month for the first 18 months, then less frequently.
Electrolyte Levels: Especially sodium and potassium.
Kidney Function Tests: Creatinine and GFR to assess disease progression.

Frequent check-ups are necessary to adjust dosage and prevent complications.

⚠️ Warnings & Precautions

Liver Toxicity: Risk of serious liver injury; not recommended for patients with significant liver impairment.
Pregnancy & Breastfeeding: Avoid during pregnancy and lactation unless absolutely necessary.
Dehydration Risk: Drink enough fluids and report signs of volume depletion.
Not for Emergency Use: Not suitable for immediate correction of hyponatremia.

📝 Summary

Tolvaptan 15 mg is a specialized medication for treating low sodium levels and delaying progression in polycystic kidney disease. While effective, it requires close medical supervision, regular monitoring of liver and kidney function, and attention to hydration. Patients must be aware of both common side effects like thirst and urination, and serious risks such as liver toxicity. Tolvaptan should be used only under a nephrologist’s guidance due to its potent effects and monitoring needs.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.