Description
🔷 PROSTATE RELIEF COMBINATION TABLET 🔷
Dual Mechanism Therapy for Effective BPH Management
💊 Composition (Per Modified-Release Tablet):
-
Tamsulosin Hydrochloride – 0.4 mg
-
Finasteride – 5 mg
🧠 Overview:
This combination tablet brings together two highly effective agents for managing Benign Prostatic Hyperplasia (BPH)—Tamsulosin, an alpha-1 adrenergic receptor antagonist, and Finasteride, a 5-alpha reductase inhibitor. This dual therapy is particularly beneficial in men with moderate to severe BPH, enlarged prostate volume, and chronic lower urinary tract symptoms (LUTS). Tamsulosin provides symptomatic relief, while Finasteride targets the underlying cause by reducing prostate size over time.
🔬 Mechanism of Action:
-
Tamsulosin 0.4 mg:
Selectively blocks alpha-1A receptors in the smooth muscles of the prostate, bladder neck, and urethra. This causes muscle relaxation, which improves urine flow and relieves LUTS such as hesitancy, urgency, and incomplete emptying. Its uroselectivity minimizes systemic side effects, especially hypotension. -
Finasteride 5 mg:
Inhibits Type II 5-alpha reductase, the enzyme responsible for converting testosterone into dihydrotestosterone (DHT)—a hormone that causes prostate enlargement. By lowering DHT levels, Finasteride leads to progressive shrinkage of the prostate, improving urinary function and reducing the risk of acute urinary retention or need for surgery.
🎯 Indications:
-
Moderate to severe Benign Prostatic Hyperplasia (BPH)
-
BPH with enlarged prostate volume
-
Chronic Lower Urinary Tract Symptoms (LUTS)
-
Prevention of BPH-related complications (e.g., urinary retention, need for surgery)
✅ Therapeutic Benefits:
-
Tamsulosin: Rapid relief of urinary symptoms
-
Finasteride: Long-term improvement by shrinking prostate volume
-
Reduces risk of acute urinary retention
-
Minimizes need for prostate surgery
-
Improves quality of life and sleep (by reducing nocturia)
💊 Dosage & Administration:
-
Adults (Male, ≥18 years):
1 tablet once daily, preferably 30 minutes after the same meal each day
Swallow whole with water; do not crush or chew
Duration: Minimum of 6 months of continuous use for full effect of Finasteride
⚠️ Precautions & Side Effects:
-
Common Side Effects:
-
Dizziness, especially postural
-
Decreased libido, ejaculatory dysfunction
-
Breast tenderness or enlargement
-
Headache or nasal congestion
-
-
Serious (Rare):
-
Allergic reactions (rash, swelling)
-
Depression or mood changes
-
Intraoperative Floppy Iris Syndrome (with cataract surgery)
-
Risk of high-grade prostate cancer (Finasteride-related; controversial)
-
-
Contraindications:
-
Women and children (especially during pregnancy—Finasteride is teratogenic)
-
Severe hepatic insufficiency
-
Caution in patients taking antihypertensives
-
🧪 Monitoring Guidelines:
-
PSA levels should be checked before and during treatment (Finasteride lowers PSA)
-
Monitor blood pressure, especially in the initial weeks
-
Assess LUTS using IPSS (International Prostate Symptom Score)
-
Periodic prostate examinations recommended
🛡️ Storage Instructions:
-
Store below 25°C, in a dry place
-
Protect from light and moisture
-
Keep out of reach of children and women of childbearing age
📝 Conclusion:
The Tamsulosin + Finasteride combination offers a comprehensive, dual-action approach for managing BPH—addressing both the symptoms and the structural causes of prostate enlargement. Ideal for long-term use in patients needing both immediate symptom relief and disease progression control.
Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.
