Description
🛡️ ALBENDAZOLE 400 mg TABLET
Trusted Broad-Spectrum Deworming Solution
COMPOSITION:
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Albendazole 400 mg
(Available as chewable or conventional tablet)
WHAT IS ALBENDAZOLE 400 mg?
Albendazole 400 mg is a broad-spectrum anthelmintic (anti-worm medication) used to treat a wide variety of intestinal and tissue parasitic infections. It is especially effective against nematodes (roundworms), cestodes (tapeworms), and certain protozoal infections. As a single-dose or short-course therapy, Albendazole is widely used in routine deworming and public health programs, particularly in areas with high parasitic burden.
MECHANISM OF ACTION:
Albendazole is part of the benzimidazole class of antiparasitic drugs. It works by:
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Inhibiting microtubule polymerization in parasitic cells through binding to β-tubulin.
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Blocking glucose uptake in parasites, leading to energy depletion.
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Causing paralysis and death of the worm due to metabolic failure.
Albendazole is metabolized in the liver into its active form, albendazole sulfoxide, which provides both intestinal and systemic efficacy.
INDICATIONS:
Albendazole 400 mg is indicated for the treatment of:
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Ascariasis (roundworm)
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Enterobiasis (pinworm)
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Trichuriasis (whipworm)
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Ancylostomiasis / Necatoriasis (hookworm)
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Taeniasis (tapeworm)
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Hymenolepiasis
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Strongyloidiasis
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Giardiasis (off-label in some regions)
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Neurocysticercosis (with adjunct therapy)
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Echinococcosis (hydatid disease) – longer-duration treatment
DOSAGE & ADMINISTRATION:
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Adults and Children over 2 years:
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Single 400 mg tablet for most intestinal infections
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Children 1–2 years:
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200 mg (half dose), under medical supervision
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May be repeated in 2–3 weeks if reinfection is likely
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Best taken with food, especially a fatty meal to improve absorption in systemic infections
Always follow healthcare provider instructions for chronic or tissue-based infections.
ADVANTAGES:
✅ Broad-spectrum efficacy against common intestinal parasites
✅ Single-dose treatment improves compliance
✅ Safe for use in children and adults
✅ Essential for mass deworming programs
✅ Improves growth, nutrition, and cognitive performance in infected children
PRECAUTIONS:
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Not recommended in pregnancy, especially during the first trimester
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Use cautiously in hepatic impairment
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For long-term therapy (e.g., neurocysticercosis or echinococcosis), monitor liver function and blood counts
POSSIBLE SIDE EFFECTS:
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Common: Abdominal pain, nausea, dizziness, headache
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Occasional: Diarrhea, vomiting, flatulence, fatigue
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Rare (long-term use): Elevated liver enzymes, mild alopecia, bone marrow suppression, hypersensitivity reactions
CONTRAINDICATIONS:
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Hypersensitivity to albendazole or other benzimidazoles
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Pregnancy (especially first trimester)
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Severe liver disease
STORAGE INSTRUCTIONS:
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Store below 25°C, protected from light and moisture
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Keep out of reach of children
DISCLAIMER:
This information is for educational purposes only. Always consult a licensed medical professional before using any medication.
