Description
🧬 ALBENDAZOLE 400 mg SUSPENSION
Broad-Spectrum Deworming Solution in Liquid Form
COMPOSITION:
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Albendazole 400 mg per 10 mL oral suspension
WHAT IS IT?
Albendazole 400 mg suspension is a broad-spectrum anthelmintic in liquid form, designed for single-dose oral treatment of parasitic worm infestations. It is particularly useful for children and adults who prefer or require a non-tablet formulation. Albendazole acts against a variety of intestinal and systemic helminths, providing fast and effective deworming therapy.
HOW IT WORKS (MECHANISM OF ACTION):
Albendazole works by targeting parasite microtubules, essential for energy metabolism. It:
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Inhibits tubulin polymerization, disrupting microtubule formation.
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Interferes with glucose uptake in helminths, leading to energy depletion.
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Causes immobilization and death of the parasite.
After oral administration, albendazole is metabolized in the liver to albendazole sulfoxide, the active systemic form.
INDICATIONS:
Albendazole 400 mg suspension is indicated for the treatment of:
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Ascariasis (roundworms)
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Enterobiasis (pinworms)
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Trichuriasis (whipworms)
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Hookworm infections (Ancylostomiasis, Necatoriasis)
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Taeniasis (tapeworms)
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Hymenolepiasis
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Strongyloidiasis
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Giardiasis (as off-label use in some cases)
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Cutaneous larva migrans
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Hydatid disease (in systemic treatment regimens)
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Neurocysticercosis (with adjunctive therapy)
DOSAGE & ADMINISTRATION:
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Children >2 years and Adults:
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Single dose of 10 mL (400 mg) orally
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Children 1–2 years:
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Half dose (5 mL or 200 mg), based on clinical judgment
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May be repeated in 2–3 weeks in high-risk areas or reinfection
Shake bottle well before each use.
Can be taken with or without food, though fatty meals enhance absorption for systemic infections.
KEY ADVANTAGES:
✅ Easy-to-administer liquid form
✅ Effective against a wide range of helminths
✅ Single-dose treatment in most cases
✅ Suitable for mass deworming programs
✅ Appropriate for both children and adults
PRECAUTIONS:
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Not recommended in pregnancy, especially in the first trimester
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Use with caution in patients with liver impairment
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Monitor liver function and blood counts during prolonged or repeated use
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Consult a doctor if symptoms persist or for systemic infections
POSSIBLE SIDE EFFECTS:
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Common: Abdominal pain, nausea, dizziness, headache
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Occasional: Vomiting, diarrhea, fatigue
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Rare (long-term use): Elevated liver enzymes, reversible alopecia, leukopenia, rash
CONTRAINDICATIONS:
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Hypersensitivity to albendazole or benzimidazoles
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Pregnant women, especially during the first trimester
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Severe hepatic dysfunction
STORAGE CONDITIONS:
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Store at or below 25°C, away from light and moisture
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Keep tightly closed and out of reach of children
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Do not use beyond the expiry date
DISCLAIMER:
This summary is for educational and informational purposes only. Always consult a licensed healthcare provider before administering any medication, especially in children or for repeated use.
